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Author Guidelines


RARE Journal is electronic journal and all articles are only online published. Submission is only online and stepwise guided. All journal correspondence takes place only by e-mail. Manuscripts are submitted by one of the authors. He/she takes responsibility for the article during submission and peer review.

File formats

The following file formats are acceptable for the manuscript documents:

  • Microsoft word (DOC, DOCX)
  • Open office writer (ODT)
  • Rich text format (RTF)

Submission declaration

RARE Journal submission implies that the material described has not been published previously (except as part of a published lecture, academic thesis, or in the cases described in the Overlapping publications section of Ethical Policy), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in any form, in English or in any other language, without the written consent of the copyright-holder.

The submission implies that all listed authors have read and agreed to the manuscript content, and that any experimental research that is reported has been performed with the approval of an appropriate ethics committee. Any experimental research under any circumstances must follow both national laws and internationally recognised guidelines. Identifying information (including names, initials, or hospital numbers) of study participants should not be published under any circumstances. It is the authors’ responsibility to respect the patients’ right of privacy, as well as the national and international legal framework on this issue.

Changes to authorship

After being accepted for publication, the material can not be changed in terms of addition, deletion, or rearrangement of author names in the authorship.

Submission cover letter

Corresponding author is requested to include a short cover letter when initially submitting the manuscript for publication. It should explain why the manuscript should be published in the journal, as well as elaborating on any issues relating to the editorial policies, and declaring any potential competing interests.

Authors are requested to provide names and contact details (e-mail addresses) of 5 preferred reviewers for their manuscript. Any suggested peer reviewers should not have published with any of the authors of the manuscript within the past five years, should not be current collaborators, and should not be members of the same research institution. All suggested reviewers will be considered alongside potential reviewers recommended by the RARE Journal Editorial staff. Authors could also indicate a list of non-preferred reviewers.

General Requirements for Authors

Publication-Specific Guidelines

Research articles

Case reports

Systematic reviews and meta-analyses

Reports of clinical practice guidelines

Reports of health technology assessment

Reports of epidemiological registries



Letters to Editors

Meeting and project reports


Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  1. The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
  2. The submission file is in OpenOffice, Microsoft Word, or RTF document file format.

  3. Where available, URLs for the references have been provided.
  4. The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines, which is found in About the Journal.
  5. The corresponding author is clearly indicated. His/her contact details are correctly mentioned.
  6. All required statements and declarations have been provided.
  7. The abstract is up to 290 words.

Copyright Notice

In submitting this article to Rare Diseases and Orphan Drugs. An International Journal of Public Health author certifies  that:

1) he/she is authorized by co-authors to enter into these arrangements;
2) he/she grants Istituto Superiore di Sanità a license to publish the article and identify itself as the original publisher;
3) he/she warrant, on behalf of co-authors, that:
  • the article is original, not in the public domain and has not been published in any other journal or book, is not being considered for publication elsewhere in any form and will not be submitted for such consideration while under review by this journal;
  • he/she is they are the sole author(s) and proprietor(s) of the article and have full power to enter into this agreement and in granting rights to the Istituto Superiore di Sanità are not in breach of any other obligation;
  • nothing in the article is obscene, defamatory, libelous, or otherwise unlawful, violates any right of privacy or infringes any intellectual property rights (including without limitation copyright, patent, or trademark) or other rights of any kind of any person or entity;
  • nothing in the article infringes any duty of confidentiality which the author(s) may owe to another party or violates any contract, express or implied, that the author(s) may have entered into, and all of the institutions where the work, as reflected in the article, was performed have authorized publication;
  • to his /hers/theirs-and currently accepted scientific knowledge all statements contained in it purporting to be facts are true and does not contain any material or instructions that might cause harm or injury.

4) and he/she agrees to the following license agreement:

  • the article will be published Open Access in the Rare Diseases and Orphan Drugs An International Journal of Public Health (RARE Journal) by the Istituto Superiore di Sanità under the terms of the Creative Commons license Attribution-NonCommercial-NoDerivs 3.0 (

Full license


Privacy Statement

Manuscripts will be reviewed with due respect for authors’ confidentiality. Reviewers also have rights to confidentiality, which must be respected by the editor. Confidentiality may have to be breached if dishonesty or fraud is alleged but otherwise must be honored. RARE Journal editors won’t disclose information about manuscripts (including their receipt, content, status in the reviewing process, criticism by reviewers, or ultimate fate) to anyone other than the authors and reviewers. This includes requests to use the materials for legal proceedings.

RARE Journal makes clear to the reviewers that manuscripts sent for review are privileged communications and are the private property of the authors. Therefore, reviewers and members of the editorial staff will respect the authors’ rights by not publicly discussing the authors’ work or appropriating their ideas before the manuscript is published. Reviewers are not allowed to make copies of the manuscript for their files and are prohibited from sharing it with others, except with the editor’s permission. Reviewers destroy copies of manuscripts after submitting reviews. Editors are not keeping copies of rejected manuscripts.

Reviewer comments are not be published without permission of the reviewer, author, and editor.

Identifying information (including names, initials, or hospital numbers) of study participants should not be published under any circumstances. It is the authors’ responsibility to respect the patients’ right of privacy, as well as the national and international legal framework on this issue.